|Statement||Compiled by Nick S. Semenuk and Helen Zimmerberg.|
|Contributions||Zimmerberg, Helen, joint author.|
|LC Classifications||Z5524.A337 S45|
|The Physical Object|
|Pagination||ix, 384 p. (p. 384 blank)|
|Number of Pages||384|
|LC Control Number||77022802|
Cyclic Amp - People Of The Book - Music. Skip to main content Hello, Sign in. Account & Lists Returns & Orders. Try Prime Cart. CDs & Vinyl Go Search Hello. Cyclic AMP. New York, Academic Press, (OCoLC) Online version: Robison, G. Alan, Cyclic AMP. New York, Academic Press, (OCoLC) Document Type: Book: All Authors / Contributors: G Alan Robison; Reginald W Butcher; . Explore releases from Cyclic Amp at Discogs. Shop for Vinyl, CDs and more from Cyclic Amp at the Discogs Marketplace. Although research relating cyclic AMP metabol ism to the development and manifestations of the immune response and the control of mammalian cell growth is relatively recent, the growth of knowledge in these areas has been rapid and there is already a considera ble amount of empirical information.
Myocardial stress and injury invariably promote remodeling of the cardiac tissue, which is associated with cardiomyocyte death and development of fibrosis. The fibrotic process is initially triggered by the differentiation of resident cardiac fibroblasts into myofibroblasts. These activated fibroblasts display increased proliferative capacity and secrete large amounts of extracellular matrix. Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger important in many biological processes. cAMP is a derivative of adenosine triphosphate (ATP) and used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent should not be confused with 5'-AMP-activated protein kinase (AMP . It was demonstrated that F-X did not increase the cyclic AMP and cyclic GMP levels in the jejunal and the ileal mucosa at 8 and 24 hr after F-X treatment. The results obtained in this work suggest that F-X-induced diarrhea is not mediated by the cyclic nucleotide system. Abstract: The ability to sense and respond to changing environments is essential for all organisms, and this process is mediated through signal transduction. The small molecules t.
Cyclic AMP (cAMP)-driven mechanisms are central to the pathogenesis of polycystic kidney disease (PKD). Cyclic AMP stimulates both fluid secretion and cell proliferation, making abnormal cAMP-regulated pathways key targets for PKD therapy. The success . The best known is the c-AMP dependant protein kinase A (PKA), but also include cyclic-nucleotide gated ion channels (CNGCs) and the recently discovered Rap1-guanine nucleotide exchange factor (Epac), three effectors known to mediate a multitude of cAMP signalling pathways. (Figure 2). Synthesis. Cyclic di-AMP is synthesized by a membrane-bound diadenylate cyclase (also called diadenylyl cyclase, CdA, and DAC) enzyme called CdaA (DacA). DacA condenses two ATP molecules to make c-di-AMP, releasing 2 pyrophosphates in the process. DacA requires a manganese or cobalt metal ion cofactor. Most bacteria possess only one DAC enzyme, but some bacteria like B. subtilis possess . Cyclic adenosine 3′,5′-monophosphate (cAMP) was the first second messenger to be identified and plays fundamental roles in cellular responses to many hormones and neurotransmitters (Sutherland and Rall ).The intracellular levels of cAMP are regulated by the balance between the activities of two enzymes (see Fig. 1): adenylyl cyclase (AC) and cyclic nucleotide phosphodiesterase (PDE).